less active enantiomer — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10480	Bay 41-4109 (less active enantiomer)		HBV
	Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent HBV inhibitor (IC50: 53 nM).		HBV
T11129L	Duvelisib (R enantiomer) hydrochloride	IPI-145 R enantiomer HCl,Duvelisib (R enantiomer) hydrochloride(1261590-48-0 Free base),INK1197 R enantiomer HCl	PI3K
	Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) is a PI3K inhibitor. Duvelisib (R enantiomer) hydrochloride is the less active enantiomer of Duvelisib.		PI3K
T12831	SAR405 R enantiomer		Others
	SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is an inhibitor of PIK3C3/Vps34.		Others
T20191	(-)-Camphoric acid	L-Camphoric acid,Camphoric acid, (-)-	GluR
	(-)-Camphoric acid (L-Camphoric acid) is a less active enantiomer of Camphoric acid which induces GluR expression.		GluR
T22450	Tyrphostin B44, (+) enantiomer		EGFR
	Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer.		EGFR
T12814	(S)-Tenofovir	(S)-PMPA,(S)-GS 1278,(S)-TDF	Others
	(S)-Tenofovir ((S)-PMPA) is the less active S-enantiomer of Tenofovir which is a nucleotide reverse transcriptase inhibitor.		Others
T10376	ARS-1630		Ras
	ARS-1630 is a mutant K-ras G12C inhibitor. It is a less active enantiomer of ARS-1620.		Ras
T13140	Umbralisib R-enantiomer	TGR-1202 R-enantiomer,RP5264 R-enantiomer	PI3K
	Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202. The IC50 of Umbralisib R-enantiomers against δPI3 kinase is at least 20 times lower than that of the in...		PI3K
T20898	(R)-Propranolol hydrochloride	Dexpropranolol hydrochloride,(R)-(+)-Propranolol	Adrenergic Receptor
	(R)-Propranolol hydrochloride (Dexpropranolol hydrochloride) is the less active enantiomer of the anti-adrenoceptor (β-adrenoceptor) antagonist propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antag...		Adrenergic Receptor
TN1448	(-)-Bornyl acetate	L-(-)-Bornyl acetate,Bornyl acetate	p38 MAPK , NF-κB , JNK , Antifungal
	(-)-Bornyl acetate (L-(-)-Bornyl acetate) is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate isolates from hyssop oil and possesses antifungal activity. (-)-Bornyl acetate shows highly active whitening...		p38 MAPK , NF-κB , JNK , Antifungal
T13438	(R,S)-Ivosidenib	(R,S)-AG-120	Opioid Receptor
	(R,S)-Ivosidenib is the less active enantiomer of Ivosidenib .		Opioid Receptor
T13450	(S)-GNE-140		Others
	(S)-GNE-140 is the less active enantiomer of GNE-140.		Others
T11156	Nazartinib S-enantiomer	EGF816 (S-enantiomer)	Others
	Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib.		Others
T10856	Cobimetinib (R-enantiomer)	XL-518 R-enantiomer,Cobimetinib R-enantiomer,GDC-0973 R-enantiomer	Others
	Cobimetinib R-enantiomer is the less active R-enantiomer of Cobimetinib which is a selective MEK inhibitor.		Others
T13426L	(3S,4S)-Tofacitinib		Others
	(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.		Others
T26371	(2S,3R)-LP99
	(2S,3R)-LP99 is a less active enantiomer of LP99.
T10564	(8R,9S)-Talazoparib	(8R,9S)-BMN-673	Others
	(8R,9S)-Talazoparib is Talazoparib enantiomer , less active than Talazoparib on the inhibition of PARP1 (IC50: 144 nM).		Others
T12636	(R)-(+)-Anatabine		Others
	(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.		Others
T11335	Fulvestrant (S enantiomer)	ZM 182780 S enantiomer,ICI 182780 S enantiomer,Fulvestrant S enantiomer,ZD 9238 S enantiomer	Others
	Fulvestrant S enantiomer is the less active S enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM.		Others
T12635	(R)-Plevitrexed	(R)-ZD 9331,(R)-BGC9331	Others
	(R)-Plevitrexed is a less active enantiomer of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).		Others